The NCC-1701 was a Federation Constitution class heavy cruiser that was in service with Starfleet in the mid to late 23rd century. In the course of her career, the Enterprise became the most celebrated starship of her time. The Enterprise was destroyed over the Genesis Planet in 2285 when Kirk activated the ship's auto destruct sequence o prevent the Enterprise from falling into the hands of the Klingons! Most famous Captain of the Enterprise was James T. Kirk!
The NCC-1701-D is a 24th century starship in the Star Trek fictional universe and the setting of the Star Trek: The Next Generation television series. It's a Galaxy class ship and the fifth Federation starship in the Star Trek universe to carry the name Enterprise. In most of its service the commanding officer of Enterprise D is Captain Jean-Luc Picard.